Gonadotropin-releasing Hormone Stimulation Test for Precocious Puberty
نویسندگان
چکیده
منابع مشابه
Gonadotropin-releasing Hormone Stimulation Test for Precocious Puberty
BACKGROUND Gonadotropin-releasing hormone (GnRH) stimulation test is the gold standard to identify central precocious puberty (CPP). This test requires multiple blood samples at different time points to measure gonadotropin levels, and is therefore expensive, time-consuming, and uncomfortable for patients. We aimed to simplify the GnRH stimulation test to require fewer blood samples. METHODS ...
متن کاملLuteinizing Hormone Secretion during Gonadotropin-Releasing Hormone Stimulation Tests in Obese Girls with Central Precocious Puberty
OBJECTIVE Girls with precocious puberty have high luteinizing hormone (LH) levels and advanced bone age. Obese children enter puberty at earlier ages than do non-obese children. We analyzed the effects of obesity on LH secretion during gonadotropin-releasing hormone (GnRH) tests in girls with precocious puberty. METHODS A total of 981 subjects with idiopathic precocious puberty who had underg...
متن کاملThe genes associated with gonadotropin-releasing hormone-dependent precocious puberty
Human puberty is a complex, coordinated biological process with multiple levels of regulations. The timing of puberty varies greatly in children and is influenced by both environmental and genetic factors. The key genes of pubertal onset, KISS1, GPR54, GNRH1 and GNRHR, may be major causal factors underlying gonadotropin-releasing hormone-dependent precocious puberty (GDPP). Two gain-of-function...
متن کاملTREATMENT OF PRECOCIOUS PUBERTY BY A LONG-ACTING GONADOTROPIN-RELEASING HORMONE ANALOGUE IN CHILDREN
The GnRH analogue has been shown to be effective in the treatment of precocious puberty when given as a daily subcutaneous injection. We studied the effectiveness of a long-acting GnRH analogue, Triptoreline, for the treatment of central precocity, by suppressing gonadotropin and estradiol secretion in three children with true precocious puberty. One month after single dose intramuscular i...
متن کاملFactors that predict a positive response on gonadotropin-releasing hormone stimulation test for diagnosing central precocious puberty in girls
PURPOSE The rapid increase in the incidence of precocious puberty in Korea has clinical and social significance. Gonadotropin-releasing hormone (GnRH) stimulation test is required to diagnose central precocious puberty (CPP), however this test is expensive and time-consuming. This study aimed to identify factors that can predict a positive response to the GnRH stimulation test. METHODS Clinic...
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ژورنال
عنوان ژورنال: Annals of Laboratory Medicine
سال: 2011
ISSN: 2234-3806,2234-3814
DOI: 10.3343/kjlm.2011.31.4.244